What type of testing is recommended when using Adefovir Dipivoxil (Hepsera)?

Adefovir Dipivoxil is an antiviral medication used primarily for the treatment of chronic hepatitis B. When initiating therapy with Adefovir, important considerations include both liver and kidney health due to the potential adverse effects on these organs.

Liver function testing is essential to monitor the liver enzymes and overall function, as the primary indication for Adefovir is related to hepatic health. Detecting any deterioration in liver function can help in mitigating complications associated with hepatitis B treatment.

Moreover, testing for HIV is critical before starting Adefovir therapy. This is because Adefovir can be ineffective in patients with HIV and may even lead to the development of drug-resistant HIV strains if it is used improperly. Therefore, confirming the patient's HIV status ensures that the treatment plan is suitable and avoids potential risks associated with concurrent HIV infection.

By committing to both liver function and HIV testing prior to therapy initiation, clinicians can ensure the safety and efficacy of Adefovir Dipivoxil treatment for patients with chronic hepatitis B.