What kind of infections are integrase inhibitors used to treat?

Integrase inhibitors are specifically designed to target and inhibit the activity of the integrase enzyme, which is crucial for the replication of retroviruses, particularly HIV (Human Immunodeficiency Virus). These agents play a vital role in antiretroviral therapy by blocking the integration of viral DNA into the host cell's genome, thus preventing the virus from replicating and spreading throughout the body.

The mechanism of action of integrase inhibitors is highly specific to retroviruses, distinguishing them from treatments used for other types of infections such as fungal, bacterial, or protozoal infections. Fungal infections are typically addressed with antifungals, bacterial infections with antibiotics, and protozoal infections with antiparasitics. Therefore, integrase inhibitors are primarily indicated for the treatment of retroviral infections, making this the correct answer.