What is the recommended use of ganciclovir?

Ganciclovir is an antiviral medication specifically indicated for the treatment of infections caused by cytomegalovirus (CMV). It is particularly important for patients who are immunocompromised, such as those with HIV/AIDS, organ transplant recipients, or patients undergoing chemotherapy. The intravenous route of administration allows for higher systemic concentrations of the drug to effectively target the virulent CMV, which can lead to severe complications, including retinitis and organ transplant rejection.

The other options relate to applications or routes not appropriate for ganciclovir. It is not indicated for topical use against skin infections, systemic bacterial infections, or oral treatment of respiratory infections, as these conditions require different types of medications or antiviral agents tailored to their specific pathogens.